A comparative appraisal of three desensitising agents found in current sensitive toothpastes

Whelan, Demi (2013) A comparative appraisal of three desensitising agents found in current sensitive toothpastes. BSc dissertation, University of Portsmouth.

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    Introduction: Dentine hypersensitivity is a common dental complaint. A short sharp pain to a cold stimulus is the usual symptom. There are three theories on the aetiology and various treatments. Treatment can include the use of topical fluoride, tooth mousse and desensitising toothpastes. Desensitising toothpastes consist of various active ingredients, which work differently and are used by different manufacturers. There is much research into these treatments and their effectiveness. However, there is no collation and review of this literature.
    Aims: To investigate three ingredients present in desensitising toothpastes, Arginine, strontium acetate and potassium nitrate. Then evaluate them for effectiveness by comparing them to each other to provide patients with evidence based advice.
    Method: To find and review the most current relevant literature and critique it for reliability. An exclusion criteria was utilised to eliminate outdated and irrelevant studies. Studies investigating the agents individually and comparing them were acquired.
    Results: After critical appraisal of the agents individually they were all found to lower dentine hypersensitivity. When compared to each other the arginine and strontium acetate were found to be most almost equal in efficacy but strontium acetate having stronger results after acid challenges. Arginine was found to be more effective then potassium nitrate. Due to a lack of studies comparing potassium nitrate and strontium acetate a fair unbiased result cannot be drawn.
    Conclusion: After a discussion of results the conclusions drawn were that understanding how each ingredients works can help advising best treatment to patients. All ingredients are effective, with strontium acetate and arginine having the edge, but further research without bias is required.

    Item Type: Dissertation
    Departments/Research Groups: Faculty of Science > Portsmouth Dental Academy
    Depositing User: Jane Polwin
    Date Deposited: 21 Oct 2013 14:23
    Last Modified: 28 Jan 2015 12:30
    URI: http://eprints.port.ac.uk/id/eprint/13661

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